CNNM2 polyclonal antibody
Product Specifications
Background
Cyclin M2 is a protein in humans that is encoded by the CNNM2 gene. This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Metal transporter CNNM2; Ancient conserved domain-containing protein 2; Cyclin-M2; CNNM2; ACDP2
Swiss Prot
Q9H8M5
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 580-630 of Human CNNM2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 96 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CNNM2 polyclonal antibody detects endogenous levels of CNNM2 protein.
Applications Notes
Western blot (WB) analysis of CNNM2 polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate (40ug) Lane2:U-87MG whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug) Lane5:HepG2 whole cell lysate (40ug)
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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