RRP7A/RRP7B polyclonal antibody

RRP7A (ribosomal RNA processing 7 homolog A), also known as CGI-96 or gastric cancer antigen Zg14, is a 280 amino acid protein that contains one RRM domain. RRP7A is encoded by a gene that maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein Bcr-Abl, a potent cell proliferation activator found in several types of leukemias.

Ribosomal RNA-processing protein 7 homolog A; Gastric cancer antigen Zg14; RRP7A; CGI-96; Putative ribosomal RNA-processing protein 7 homolog B; Putative gastric cancer antigen Zg14-like protein; RRP7BP; RRP7B

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Western blot (WB) analysis of RRP7A/RRP7B polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate (40ug) Lane2:C6 whole cell lysate (40ug) Lane3:HEK293T whole cell lysate (40ug) Lane4:A549 whole cell lysate (40ug) Lane5:MCF-7 whole cell lysate (40ug)