What is the catalog number for MYLIP polyclonal antibody?

The catalog number for MYLIP polyclonal antibody is BS61709.

What sizes are available for MYLIP polyclonal antibody?

MYLIP polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does MYLIP polyclonal antibody come in?

MYLIP polyclonal antibody is available in 2 different pack sizes.

Is MYLIP polyclonal antibody in stock?

MYLIP polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MYLIP polyclonal antibody

Product Specifications

Background

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

E3 ubiquitin-protein ligase MYLIP; Inducible degrader of the LDL-receptor; Idol; Myosin regulatory light chain interacting protein; MIR; RING-type E3 ubiquitin transferase MYLIP; MYLIP; BZF1; IDOL; BM-023; PP5242

Swiss Prot

Q8WY64

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 150-200 of Human MYLIP.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 49 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MYLIP polyclonal antibody detects endogenous levels of MYLIP protein.

Applications Notes

Western blot (WB) analysis of MYLIP polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate (40ug) Lane2:COS-7 whole cell lysate (40ug) Lane3:MCF-7 whole cell lysate (40ug) Lane4:PC12 whole cell lysate (40ug) Lane5:CT26 whole cell lysate (40ug)