TBX2/TBX3 polyclonal antibody

The T-box (Tbx) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The Tbx gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. Tbx genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in Tbx genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/ brachyury, which is a transcription activator. The Tbx genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Western blot (WB) analysis of TBX2/TBX3 polyclonal antibody at 1:500 dilution Lane1:786-O whole cell lysate (40ug) Lane2:A549 whole cell lysate (40ug) Lane3:The fetal lung tissue lysate of Mouse (40ug) Lane4:The fetal lung tissue lysate of Rat (40ug)