TRAPPC5 polyclonal antibody
Product Specifications
Background
TRAPPC5 (trafficking protein particle complex 5), also known as TRS31, is a 181 amino acid protein belonging to the TRAPP (transport protein particle) small subunits family and the BET3 subfamily. Encoded by a gene that maps to human chromosome 19p13.2, TRAPPC5 is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. Evolutionarily conserved, TRAPPC5 plays a role in protein binding, vesicle-mediated transport and nucleotide exchange stimulation. TRAPPC5 also performs guanine nucleotide exchanger factor (GEF) functions both in vitro and in vivo.Localizing to the Golgi apparatus, TRAPPC5 is essential for endoplasmic reticulum (ER) -to-Golgi and intra-Golgi vesicle trafficking in yeast, aswell as additional transport events in mammals, such as post--Golgi trafficking.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Trafficking protein particle complex subunit 5; TRAPPC5
Swiss Prot
Q8IUR0
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 68-113 of Human TRAPPC5.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 20 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TRAPPC5 polyclonal antibody detects endogenous levels of TRAPPC5 protein.
Applications Notes
Western blot (WB) analysis of TRAPPC5 polyclonal antibody at 1:500 dilution Lane1:H9C2 whole cell lysate (40ug) Lane2:HEK293T whole cell lysate (40ug) Lane3:NIH-3T3 whole cell lysate (40ug) Lane4:PC12 whole cell lysate (40ug) Lane5:Hela whole cell lysate (40ug)
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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