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CT47 polyclonal antibody

Product Specifications

Background

CT47 (cancer/testis antigen family 47) is a 288 amino acid protein that is strongly expressed in testis and lowly expressed in placenta and in brain. The gene encoding CT47 is located on human chromosome X, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cancer/testis antigen 47A; Cancer/testis antigen 47; CT47; CT47A1; CT47.1; CT47A2; CT47.2; CT47A3; CT47.3; CT47A4; CT47.4; CT47A5; CT47.5; CT47A6; CT47.6; CT47A7; CT47.7; CT47A8; CT47.8; CT47A9; CT47.9; CT47A10; CT47.10; CT47A11; CT47.11; CT47A12; CT47.12

Swiss Prot

Q5JQC4

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human CT47.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 30 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -21°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CT47 polyclonal antibody detects endogenous levels of CT47 protein.

Applications Notes

Western blot (WB) analysis of CT47 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:RAW264.7 whole cell lysate Lane3:PC12 whole cell lysate

Host or Source

Rabbit

Available Sizes

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