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RAB41 polyclonal antibody

Product Specifications

Background

Rab 41 (Ras-related protein Rab-41) is a 222 amino acid protein that belongs to the small GTPase superfamily and the Rab family.Members of the Rab familyfunction asregulators ofmembrane trafficking. Theycycle between inactive GDP-bound and activated GTP-bound states, which iscontrolled by GTP hydrolysis-activating proteins (GAPs) . Rab 41 can be activated bythe GAP protein RN-Tre.Localizing to the Golgicomplex, Rab 41 isinvolved in protein transport and participatesin GTP binding. Existing astwo alternativelyspliced isoforms, the gene that encodesthe Rab 41 proteinmapsto human chromosome Xq13.1. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia, and Duchennemuscular dystrophy arewellknown X chromosome-linked conditionswhich affectmales more frequently asmalescarry a single X chromosome.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Ras-related protein Rab-41; RAB41

Swiss Prot

Q5JT25

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human RAB41.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 25 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

RAB41 polyclonal antibody detects endogenous levels of RAB41 protein.

Applications Notes

Western blot (WB) analysis of RAB41 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate

Host or Source

Rabbit

Available Sizes

Curated Selection

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