CMTM1 polyclonal antibody
Product Specifications
Background
Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine-like factor superfamily (CKLFSF) share similarities with both chemokine and transmembrane 4 superfamilies of signaling molecules. As a member of the CKLFSF family of proteins, CMTM1 (CKLF-like MARVEL transmembrane domain-containing protein 1), also known as CKLFSF1 (Chemokine-like factor superfamily member 1), is a 169 amino acid multi-pass membrane protein that is highly expressed in testis, therefore probably playing a role in spermatogenesis or testicular development. CMTM1 contains a CC-chemokine motif and four transmembrane segments. The gene encoding CMTM1 resides in a tight gene cluster on human chromosome 16 with CKLF, CMTM2, CMTM3 and CMTM4. There are at least sixteen isoforms of CMTM1 that are produced as a result of alternative splicing events.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CKLF-like MARVEL transmembrane domain-containing protein 1; Chemokine-like factor superfamily member 1; CMTM1; CKLFSF1
Swiss Prot
Q8IZ96
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human CMTM1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 18 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CMTM1 polyclonal antibody detects endogenous levels of CMTM1 protein.
Applications Notes
Western blot (WB) analysis of CMTM1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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