MP68 polyclonal antibody

Product Specifications

Background

MP68, also known as PLPM or C14orf2 (chromosome 14 open reading frame 2), is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD) . The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

6.8 kDa mitochondrial proteolipid; MP68; C14orf2; PRO1574

Swiss Prot

P56378

Reactivity

Human, Rat

Immunogen

A synthetic peptide corresponding to residues in Human MP68.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 9 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

MP68 polyclonal antibody detects endogenous levels of MP68 protein.

Applications Notes

Western blot (WB) analysis of MP68 pAb at 1:1000 dilution Lane1:The Brain tissue lysate of Rat (20ug) Lane2:HepG2 whole cell lysate (20ug) Lane3:HCT116 whole cell lysate (20ug)