CD101 polyclonal antibody
Product Specifications
Background
CD101 is a disulfide-linked homodimeric polypeptide. The gene encoding the CD101 antigen is identical to the gene encoding for the V7 antigen, which corresponds to a type I transmembrane protein containing seven Ig-like loops in its extracellular domain. CD101 may play an important regulatory role during T cell activation and may also be useful in combination with other markers for the diagnosis of LCH (Langerhans cell histiocytosis) . CD101 is expressed on monocytes, granulocytes, dendritic cells and at low levels on a subset of peripheral T-cells comprising both CD4+ and CD8+, as well as both CD45RA+ and CD45RO+ cells. Expression of CD101 increases upon T cell activation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Immunoglobulin superfamily member 2; IgSF2; Cell surface glycoprotein V7; Glu-Trp-Ile EWI motif-containing protein 101; EWI-101; CD101; CD101; EWI101; IGSF2; V7
Swiss Prot
Q93033
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human CD101.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 115 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD101 polyclonal antibody detects endogenous levels of CD101 protein.
Applications Notes
Western blot (WB) analysis of CD101 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:RAW264.7 whole cell lysate Lane3:H9C2 whole cell lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
