ARSD polyclonal antibody
Product Specifications
Background
Arylsulfatase D, also known as ARSD, is a 593 amino acid protein that localizes to the lysosome and belongs to the sulfatase family of bone and cartilage matrix proteins. Existing as three alternatively spliced isoforms which are expressed in liver, pancreas, kidney, heart, brain, lung and placenta, Arylsulfatase D uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The gene encoding Arylsulfatase D maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Arylsulfatase D; ASD; ARSD
Swiss Prot
P51689
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to residues in Human ARSD.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ARSD polyclonal antibody detects endogenous levels of ARSD protein.
Applications Notes
Western blot (WB) analysis of ARSD polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:sp2/0 whole cell lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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