What is the catalog number for EPX polyclonal antibody?

The catalog number for EPX polyclonal antibody is BS60713.

What sizes are available for EPX polyclonal antibody?

EPX polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does EPX polyclonal antibody come in?

EPX polyclonal antibody is available in 2 different pack sizes.

Is EPX polyclonal antibody in stock?

EPX polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

EPX polyclonal antibody

Product Specifications

Background

Eosinophil peroxidase (EPX) is an antimycobacterial protein that localizes to cytoplasmic granules of eosinophils and recruits bromide to generate a halogenating oxidant. EPX-dependent generation of hypobromous acid causes damage to tissue during inflammatory conditions that include asthma, allergies, cancer, and parasitic/helminthic infections. Human EPX gene product can form a tetramer of two light chains and two heavy chains. EPX is a major enzyme present in eosinophils and upon degranulation, becomes released into the airways of asthmatics. As a result of its cationic nature and its ability to catalyze the formation of highly toxic oxidants, EPX can induce lung injury in a JNK-dependent manner. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO) .

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Eosinophil peroxidase; EPO; EPX; EPER; EPO; EPP

Swiss Prot

P11678

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human EPX

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 81 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

EPX polyclonal antibody detects endogenous levels of EPX protein.

Applications Notes

Western blot (WB) analysis of EPX polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate