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ZNF441 polyclonal antibody

Product Specifications

Background

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain several Krüppel-type DNA binding domains that are frequently observed to be involved in sequence-specific DNA binding. ZNF441 is a 626 amino acid transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. ZNF441 localizes to the nucleus and contains 19 C2H2-type zinc fingers. ZNF441 is encoded by a gene located on chromosome 19, which contains a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. Chromosome19 is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and FcR. Key genes for eye color and hair color also map to chromosome 19.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Zinc finger protein 441; ZNF441

Swiss Prot

Q8N8Z8

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human ZNF441

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ZNF441 polyclonal antibody detects endogenous levels of ZNF441 protein.

Applications Notes

Western blot (WB) analysis of ZNF441 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:A549 whole cell lysate Lane3:PC12 whole cell lysate

Host or Source

Rabbit

Available Sizes

Curated Selection

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