B4GALT6 polyclonal antibody

β-1,4-galactosyltransferases (β-1,4-Gal-T) are type II membrane-bound glycoproteins that are substrate-specific and function to transfer galactose in a β-1,4 linkage to an acceptor sugar. There are seven members of the β-1,4-Gal-T family, all of which are directed to the Golgi apparatus through a hydrophobic sequence at the N-terminus. β-1,4-Gal-T6, also known as B4GALT6, is a 382 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and belongs to the β-1,4-galactosyltransferase family. Expressed at high levels in adrenal gland and brain and present at lower levels in lung, liver and colon, β-1,4-Gal-T6 uses magnesium or zinc to catalyze the UDP-dependent biosynthesis of glycosphingolipids. The gene encoding β-1,4-Gal-T6 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.

Beta-1,4-galactosyltransferase 6; Beta-1,4-GalTase 6; Beta4Gal-T6; b4Gal-T6; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 6; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 6 ; Including the following 1 domains:Glucosylceramide beta-1,4-galactosyltransferase; Lactosylceramide synthase; LacCer synthase; UDP-Gal:glucosylceramide beta-1,4-galactosyltransferase; B4GALT6

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Western blot (WB) analysis of B4GALT6 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:A549 whole cell lysate Lane3:sp2/0 whole cell lysate