DARC polyclonal antibody

Product Specifications

Background

Duffy protein (CD234) is the receptor for the human malarial parasite Plasmodium vivax, simian malarial parasite Plasmodium knowlesi, and can bind chemokines. Duffy is an acidic glycoprotein that carries antigenic determinants of the Duffy blood group system, which consists of four alleles, five phenotypes and five antigens. Duffy protein is detectable in endothelial cells of postcapillary venules, epithelial cells of kidney collecting ducts, lung alveoli, thyroid, and Purkinje cells in the cerebellum.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Atypical chemokine receptor 1; Duffy antigen/chemokine receptor; Fy glycoprotein; GpFy; Glycoprotein D; Plasmodium vivax receptor; CD234; ACKR1; DARC; FY, GPD

Swiss Prot

Q16570

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human DARC

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 36 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

DARC polyclonal antibody detects endogenous levels of DARC protein.

Applications Notes

Western blot (WB) analysis of DARC polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate