MED31 polyclonal antibody
Product Specifications
Background
Med31 (mediator of RNA polymerase II transcription subunit 31), also known as Soh1 or CGI-125, is a 131 amino acid protein that belongs to the mediator complex subunit 31 family. Mediator proteins serve as connectors between transcriptional activators and basal transcription machinery. Med31 is an evolutionary conserved coregulator of RNA polymerase II transcription and is a stable component of the Mediator complex. It is involved in forming a scaffold with other regulatory proteins for the assembly of a functional preinitiation complex with RNA polymerase II and general transcription factors. Med31 is required for normal levels of gene conversion during meiosis and contributes in the coordination of cellular processes by regulating the expression of larger sets of genes.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Mediator of RNA polymerase II transcription subunit 31; Mediator complex subunit 31; Mediator complex subunit SOH1; hSOH1; MED31; SOH1; CGI-125
Swiss Prot
Q9Y3C7
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to residues in Human MED31.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 16 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MED31 polyclonal antibody detects endogenous levels of MED31 protein.
Applications Notes
Western blot (WB) analysis of MED31 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:MCF-7 whole cell lysate
Host or Source
Rabbit
Available Sizes
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