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FSHB polyclonal antibody

Product Specifications

Background

Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common α subunit and a homologous but distinct β subunit. While the α subunit of FSH is involved in the binding of FSH to the receptor (follicle-stimulating hormone receptor, also known as FSHR), the β subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, posttranslational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Follitropin subunit beta; Follicle-stimulating hormone beta subunit; FSH-B; FSH-beta; Follitropin beta chain; FSHB

Swiss Prot

P01225

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human FSHB.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 15 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

FSHB polyclonal antibody detects endogenous levels of FSHB protein.

Applications Notes

Western blot (WB) analysis of FSHB polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate

Host or Source

Rabbit

Available Sizes

Curated Selection

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