TCEAL8 polyclonal antibody

TCEAL8 (transcription elongation factor A protein-like 8), also known as transcription elongation factor S-II protein-like 8, is a 117 amino acid nuclear protein that belongs to the TFS-II family and the TFA subfamily, and may be involved in transcriptional regulation. The gene that encodes TCEAL8 contains approximately 2,209 bases and maps to human chromosome Xq22.1. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of a X and Y chromosome leads to normal male development while two copies of X leads to normal female development. There are a number of conditions related to an unusual number and combination of sex chromosomes being inherited, including Turner’s syndrome, Klinefelter’s syndrome and Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Western blot (WB) analysis of TCEAL8 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate