MIEN1 polyclonal antibody
Product Specifications
Background
C35, also known as XTP4 (HBV X-transactivated gene 4) and protein C17orf37, is a 115 amino acid cytoplasmic protein that is a member of the SelWTH protein family. SelWTH proteins contain a thioredoxin-like fold and a conserved CxxC or CxxU motif, suggesting that they may play functional role in redox reactions. Although found at trace levels in normal breast ductal epithelium and testis, expression of C35 is robust in infiltrating ductal carcinomas of the breast, lobular carcinoma, as well as distant metastases of breast cancer such as liver, lung and skin. The prevalence and abundance of C35 overexpression in tumors suggest that it may be an appropriate bio-marker for diagnosis and a potential target for therapeutic intervention.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Migration and invasion enhancer 1; HBV X-transactivated gene 4 protein; HBV XAg-transactivated protein 4; Protein C35; MIEN1; C17orf37; RDX12; XTP4
Swiss Prot
Q9BRT3
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human MIEN1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 12 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MIEN1 polyclonal antibody detects endogenous levels of MIEN1 protein.
Applications Notes
Western blot (WB) analysis of MIEN1 polyclonal antibody at 1:500 dilution Lane1:MCF-7 whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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