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RETN polyclonal antibody

Product Specifications

Background

The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin) also known as ADSF, is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Resistin; Adipose tissue-specific secretory factor; ADSF; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2 Cysteine-rich secreted protein FIZZ3; RETN; FIZZ3, HXCP1, RSTN; UNQ407/PRO1199

Swiss Prot

Q9HD89

Reactivity

Human

Immunogen

A synthetic peptide corresponding to residues in Human RETN.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 12 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

RETN polyclonal antibody detects endogenous levels of RETN protein.

Applications Notes

Western blot (WB) analysis of RETN polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate Lane2:DLD whole cell lysate

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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