RETN polyclonal antibody
Product Specifications
Background
The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin) also known as ADSF, is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Resistin; Adipose tissue-specific secretory factor; ADSF; C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 2 Cysteine-rich secreted protein FIZZ3; RETN; FIZZ3, HXCP1, RSTN; UNQ407/PRO1199
Swiss Prot
Q9HD89
Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues in Human RETN.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 12 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RETN polyclonal antibody detects endogenous levels of RETN protein.
Applications Notes
Western blot (WB) analysis of RETN polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate Lane2:DLD whole cell lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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