DEFB1 polyclonal antibody
Product Specifications
Background
β-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Research indicates that human β-defensin 1 may contribute to the antimicrobial activity of airway surface fluid and may play a role in the mucosal defenses of the lung. Human β-defensin 1 shares homology with other β-defensins from human blood filtrate and is also present in nanomolar concentrations in human plasma. In addition to the antimicrobial activity of human airway epithelia, β-defensin 1 may play a role in the mucosal defenses of the lung.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Beta-defensin 1; BD-1; hBD-1; Defensin, beta 1; DEFB1; BD1, HBD1; β-defensin 1; Defensin β-1; Defensin β1
Swiss Prot
P60022
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human DEFB1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 7 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
DEFB1 polyclonal antibody detects endogenous levels of DEFB1 protein.
Applications Notes
Western blot (WB) analysis of DEFB1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat heart tissue lysate
Host or Source
Rabbit
Available Sizes
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