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Opticin polyclonal antibody

Product Specifications

Background

Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Oculoglycan; OPTC; OPT

Swiss Prot

Q9UBM4

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human Opticin.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 40 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Opticin polyclonal antibody detects endogenous levels of Opticin protein.

Applications Notes

Western blot (WB) analysis of Opticin polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Mouse heart tissue lysate Lane3:Rat heart tissue lysate

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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