IL28A polyclonal antibody
Product Specifications
Background
The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. As new cytokines are molecularly characterized, they are assigned an IL number to maintain a standard nomenclature. The interleukins are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. IL-28 and IL-29 are induced by viral infection and show antiviral activity. IL-28 may play a role in antiviral immunity through up-regulation of MHC class I antigen expression. IL-28 is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Interferon lambda-2; IFN-lambda-2; Cytokine Zcyto20; Interleukin-28A; IL-28A; IFNL2; IL28A; ZCYTO20
Swiss Prot
Q8IZJ0
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human IL28A.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 19 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IL28A polyclonal antibody detects endogenous levels of IL28A protein.
Applications Notes
Western blot (WB) analysis of IL28A polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:Raw264.7 cell lysate Lane3:Rat liver tissue lysate
Host or Source
Rabbit
Available Sizes
Curated Selection
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