CYP2C9 polyclonal antibody
Product Specifications
Background
Cytochrome P450, family 2, subfamily C polypeptides 9 and 19 are part of the CYP2C subfamily and are responsible for metabolizing many important drugs. CYP2C19 accounts for about 20% of the cytochrome p450 in adult liver. CYP2C9 contributes to the metabolism of fatty acids, prostanoids, and steroid hormones, and it may catalyze potentially toxic bioactivation reactions. A significant negative correlation (r = -0.572, P < .01) between enzyme activity and age was observed for CYP2C19, but there were no sex differences.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cytochrome P450 2C9; (R) -limonene 6-monooxygenase; (S) -limonene 6-monooxygenase; (S) -limonene 7-monooxygenase; CYPIIC9; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; S-mephenytoin 4-hydroxylase; CYP2C9; CYP2C10
Swiss Prot
P11712
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human CYP2C9.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 56 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CYP2C9 polyclonal antibody detects endogenous levels of CYP2C9 protein.
Applications Notes
Western blot (WB) analysis of CYP2C9 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Raw264.7 cell lysate Lane3:PC12 cell lysate
Host or Source
Rabbit
Available Sizes
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