ZNF25 polyclonal antibody
Product Specifications
Background
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF25 (Zinc finger protein 25), also known as Zinc finger protein KOX19, is a 456 amino acid nuclear protein that contains one KRAB domain and twelve C2H2-type zinc fingers. The gene encoding ZNF25 maps to a region of human chromosome 10 that has been a loci of interest for multiple endocrine neoplasia type 2A and 2B. There are two isoforms of ZNF25 that are produced as a result of alternative splicing events.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Zinc finger protein 25; Zinc finger protein KOX19; KOX19
Swiss Prot
P17030
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human ZNF25.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ZNF25 polyclonal antibody detects endogenous levels of ZNF25 protein.
Applications Notes
Western blot (WB) analysis of ZNF25 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:H9C2 whole cell lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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