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ZNF9 polyclonal antibody

Product Specifications

Background

Cellular nucleic acid binding protein (CNBP) is a highly conserved RNA-binding protein that plays a fundamental biological role in eukaryotic cells by increasing heterologous protein production. CNBP localizes to the nucleus of cells and functions in the brain, specifically in the anterior visceral endoderm and, subsequently, in the anterior definitive endoderm, anterior neuroectoderm, anterior mesendoderm, headfolds and forebrain. CNBP is necessary for the forebrain induction and specification, and mutations in the CNBP gene lead to severe forebrain truncation as well as various craniofacial defects due to a lack of proper morphogenetic movements of the anterior visceral endoderm during the pre-gastrulation stage. Overexpression of CNBP activates cell proliferation and stimulates the activity of the c-Myc promoter.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cellular nucleic acid-binding protein; CNBP; Zinc finger protein 9; CNBP; RNF163; ZNF9

Swiss Prot

P62633

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human ZNF9.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 19 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ZNF9 polyclonal antibody detects endogenous levels of ZNF9 protein.

Applications Notes

Western blot (WB) analysis of ZNF9 polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Raw264.7 cell lysate Lane3:Mouse brain tissue lysate

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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