SLC9A5 polyclonal antibody
Product Specifications
Background
Na+/H+ exchangers-1–6 (Na+/H+ antiporters, NHE-1–6) are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) . Excluding NHE-1, which is ubiquitously expressed, NHE isoforms 2–6 have distinct tissue- and cell type-dependent expression and inhibitiory characteristics by amiloride analogs. Human NHE-5 transcript (solute carrier family 9, isoform-5, SLC9A5) is an 896 amino acid protein that is expressed in brain, testis, spleen and skeletal muscle.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Sodium/hydrogen exchanger 5; Na (+) /H (+) exchanger 5; NHE-5; Solute carrier family 9 member 5; NHE5
Swiss Prot
Q14940
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human SLC9A5.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 90 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SLC9A5 polyclonal antibody detects endogenous levels of SLC9A5 protein.
Applications Notes
Western blot (WB) analysis of SLC9A5 polyclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate Lane2:NIH-3T3 whole cell lysate Lane3:Rat brain tissue lysate
Host or Source
Rabbit
Available Sizes
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