RAB8B polyclonal antibody
Product Specifications
Background
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab superfamilies exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. Rab 8B (Ras-related protein Rab-8B) is a 207 amino acid lipid anchor that localizes to the cytoplasmic side of the cell membrane and belongs to the Rab family and small GTPase superfamily. Rab 8B may be involved in neurotransmitter release and vesicular trafficking, and is encoded by a gene located on human chromosome Rab 8B and mouse chromosome 9 C.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Ras-related protein Rab-8B
Swiss Prot
Q92930
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human RAB8B.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RAB8B polyclonal antibody detects endogenous levels of RAB8B protein.
Applications Notes
Western blot (WB) analysis of RAB8B polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate
Host or Source
Rabbit
Available Sizes
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