CD42c polyclonal antibody
Product Specifications
Background
CD42a is a single-chain membrane glycoprotein that forms a noncovalent complex with CD42b. CD42b, also known as glycoprotein Ib a (GPIb a) is a membrane glycoprotein that is composed of a and b chains. The CD42b b chain is also designated CD42c, and is expressed on platelets and megakaryoctes. CD42a and CD42b are also present on platelets and mega-karyocytes, and the complex is a major component of the platelet surface. The complex acts as a receptor for von Willebrand’s factor and as a von Willebrand’s factor-dependent adhesion receptor.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Platelet glycoprotein Ib beta chain; GP-Ib beta; GPIb-beta; GPIbB; Antigen CD42b-beta; CD42c; GP1BB
Swiss Prot
P13224
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human CD42c.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 22 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD42c polyclonal antibody detects endogenous levels of CD42c protein.
Applications Notes
Western blot (WB) analysis of GP1BB polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:Rat heart tissue lysate
Host or Source
Rabbit
Available Sizes
Curated Selection
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