CD42c polyclonal antibody

Product Specifications

Background

CD42a is a single-chain membrane glycoprotein that forms a noncovalent complex with CD42b. CD42b, also known as glycoprotein Ib a (GPIb a) is a membrane glycoprotein that is composed of a and b chains. The CD42b b chain is also designated CD42c, and is expressed on platelets and megakaryoctes. CD42a and CD42b are also present on platelets and mega-karyocytes, and the complex is a major component of the platelet surface. The complex acts as a receptor for von Willebrand’s factor and as a von Willebrand’s factor-dependent adhesion receptor.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Platelet glycoprotein Ib beta chain; GP-Ib beta; GPIb-beta; GPIbB; Antigen CD42b-beta; CD42c; GP1BB

Swiss Prot

P13224

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human CD42c.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 22 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

CD42c polyclonal antibody detects endogenous levels of CD42c protein.

Applications Notes

Western blot (WB) analysis of GP1BB polyclonal antibody at 1:500 dilution Lane1:Jurkat whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:Rat heart tissue lysate