ANP32D polyclonal antibody

Product Specifications

Background

ANP32D (acidic (leucine-rich) nuclear phosphoprotein 32 family, member D), also known as PP32R2 (phosphoprotein 32-related protein 2) or tumorigenic protein pp32r2, is a 131 amino acid protein that contains 3 leucine-rich repeats and belongs to the ANP32 family. ANP32D shares 89.3% amino acid sequence identity with ANP32A, a tumor suppressor that inhibits a variety of cancers, such as prostate and breast cancers. Although similar to ANP32A, ANP32D is tumorigenic and is preferentially expressed in prostatic cancer. Conversely, it is uncertain that ANP32D is neurally expressed. Intronless, ANP32D may be a pseudogene that is expressed in pathological situations and may also modulate the oncogenic potential of human prostate cancer. A

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Cidic leucine-rich nuclear phosphoprotein 32 family member D; Phosphoprotein 32-related protein 2; Tumorigenic protein pp32r2; PP32R2

Swiss Prot

O95626

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human ANP32D.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 15 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

ANP32D polyclonal antibody detects endogenous levels of ANP32D protein.

Applications Notes

Western blot (WB) analysis of ANP32D polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat iver tissue lysate