What is the catalog number for TGFα polyclonal antibody?

The catalog number for TGFα polyclonal antibody is BS60009.

What sizes are available for TGFα polyclonal antibody?

TGFα polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does TGFα polyclonal antibody come in?

TGFα polyclonal antibody is available in 2 different pack sizes.

Is TGFα polyclonal antibody in stock?

TGFα polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

TGFα polyclonal antibody

Product Specifications

Background

Transforming growth factor-α (TGFα) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGFα is 33% homologous at the amino acid level to epidermal growth factor (EGF) . TGFα binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor-b. TGFα is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFα bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Protransforming growth factor alpha; Transforming growth factor alpha; TGF-alpha; EGF-like TGF; ETGF; TGF type 1; TGFA; TGF α

Swiss Prot

P01135

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human TGFα.

Conjugation

Unconjugated

Related Pathways

TGFβ Smad signaling

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 17 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

TGFα polyclonal antibody detects endogenous levels of TGFα protein.

Applications Notes

Western blot (WB) analysis of TGFα polyclonal antibody at 1:500 dilution Lane1:THP-1 whole cell lysate Lane2:Mouse brain tissue lysate Lane3:Rat brain tissue lysate