ZNF682 polyclonal antibody

Product Specifications

Background

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 682 (ZNF682) is a 498 amino acid member of the Krueppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF682 contains eleven C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation. Two isoforms of ZNF682 exist as a result of alternative splicing events.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Zinc finger protein 682

Swiss Prot

O95780

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 61-106 of Human ZNF682.

Conjugation

Unconjugated

Applications

WB ICC

Dilution

WB: 1:500~1:1000 ICC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .