SUHW1 polyclonal antibody

Product Specifications

Background

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. SUHW1 (Suppressor of hairy wing homolog 1), also known as ZNF280A (Zinc finger protein 280A), 3'OY11.1, ZNF636 or ZNF280, is a 542 amino acid protein that contains four C2H2-type zinc fingers. Localized to the nucleus, SUHW1 is thought to function as a transcription factor that may mediate transcriptional regulation events.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Zinc finger protein 280A; 3'OY11.1; Suppressor of hairy wing homolog 1; Zinc finger protein 636; ZNF280A; SUHW1; ZNF280; ZNF636

Swiss Prot

P59817

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 491-536 of Human SUHW1.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 61 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

SUHW1 polyclonal antibody detects endogenous levels of SUHW1 protein.

Applications Notes

Western blot (WB) analysis of SUHW1 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:NIH-3T3 cell lysate Lane3:Rat kidney tissue lysate