SSBP2 polyclonal antibody
Product Specifications
Background
The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, as well as in mitochondria, bacteria and viruses. SSBP2 (single-stranded DNA binding protein 2), also known as SSDP2, is a 361 amino acid protein that localizes to the nucleus and contains one LisH domain. Expressed ubiquitously, SSBP2 is thought to induce growth arrest in cancer cells and may, therefore, function as a potent tumor suppressor. The gene encoding SSBP2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Defects in chromosome 5-associated genes are related to the pathogenesis of Cockayne syndrome, familial adenomatous polyposis and Treacher Collins syndrome.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Single-stranded DNA-binding protein 2; Sequence-specific single-stranded-DNA-binding protein 2; SSBP2; SSDP2
Swiss Prot
P81877
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 2-47 of Human SSBP2.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 38 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SSBP2 polyclonal antibody detects endogenous levels of SSBP2 protein.
Applications Notes
Western blot (WB) analysis of SSBP2 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:NIH-3T3 cell lysate Lane3:Rat kidney tissue lysate
Host or Source
Rabbit
Available Sizes
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