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SERPINB4 polyclonal antibody

Product Specifications

Background

SERPINB4 is also called squamous cell carcinoma antigen 2 (SCCA-2) or leupin. It directly inhibits human granzyme proteolytic activity and that overexpression of SERPINB4 in HeLa cells inhibits recombinant granzyme-induced as well as NK cell-mediated cell death.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Serpin B4; Leupin; Peptidase inhibitor 11; PI-11; Squamous cell carcinoma antigen 2; SCCA-2; PI11; SCCA2

Swiss Prot

P48594

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 305-350 of Human SERPINB4.

Conjugation

Unconjugated

Applications

WB ICC

Dilution

WB: 1:500~1:1000 ICC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 45 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

SERPINB4 polyclonal antibody detects endogenous levels of SERPINB4 protein.

Applications Notes

Western blot (WB) analysis of SERPINB4 polyclonal antibody at 1:500 dilution Lane1:THP-1 cell lysate Lane2:sp2/0 cell lysate Lane3:PC12 cell lysate

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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