PSD-93 polyclonal antibody
Product Specifications
Background
The postsynaptic density protein (PSD) -93 and related membrane associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. PSD-93 (also designated channel associated protein of synapse-110 or chapsyn-110) occurs only at postsynaptic sites in hippocampal neurons. PSD-95 and PSD-93 mediate ion channel clustering in heterologous cells and are believed to cluster and anchor NMDA receptors at the synapse. The glutamate receptor subunit, delta2, binds specifically to PSD-93, which is enriched in Purkinje neuron cell bodies and dendrites. In addition, PSD-93 clusters delta2 when they are coexpressed and they are colocalized at parallel fiber synapses.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Disks large homolog 2; Channel-associated protein of synapse-110; Chapsyn-110; Chapsyn110; Chapsyn 110; Postsynaptic density protein PSD-93; PSD93; DLG2
Swiss Prot
Q15700
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 647-692 of Human PSD-93.
Conjugation
Unconjugated
Applications
WB ICC
Dilution
WB: 1:500~1:1000 ICC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 110 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PSD-93 polyclonal antibody detects endogenous levels of PSD-93 protein.
Applications Notes
Western blot (WB) analysis of PSD-93 polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:PC12 cell lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1085512-01 0.02 mg (E-Coli)
Recombinant Rickettsia canadensis Nucleoside diphosphate kinase (ndk)
Sign In for Pricing
View Details MBS1085512-02 0.1 mg (E-Coli)
Recombinant Rickettsia canadensis Nucleoside diphosphate kinase (ndk)
Sign In for Pricing
View Details MBS1085512-03 0.02 mg (Yeast)
Recombinant Rickettsia canadensis Nucleoside diphosphate kinase (ndk)
Sign In for Pricing
View Details MBS1085512-04 0.1 mg (Yeast)
Recombinant Rickettsia canadensis Nucleoside diphosphate kinase (ndk)
Sign In for Pricing
View Details MBS1085512-05 0.02 mg (Baculovirus)
Recombinant Rickettsia canadensis Nucleoside diphosphate kinase (ndk)
Sign In for Pricing
View Details MBS1085512-06 0.02 mg (Mammalian-Cell)
Recombinant Rickettsia canadensis Nucleoside diphosphate kinase (ndk)
Sign In for Pricing
View Details