What is the catalog number for PDE4C polyclonal antibody?

The catalog number for PDE4C polyclonal antibody is BS5844.

What sizes are available for PDE4C polyclonal antibody?

PDE4C polyclonal antibody is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does PDE4C polyclonal antibody come in?

PDE4C polyclonal antibody is available in 2 different pack sizes.

Is PDE4C polyclonal antibody in stock?

PDE4C polyclonal antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PDE4C polyclonal antibody

Product Specifications

Background

Phosphodiesterases (PDE) hydrolyze cAMP to 5’AMP and thus play a critical role in the regulation of intracellular cAMP. Division of the PDE superfamily by sequence homology and enzymatic properties yields 11 PDE families. A unique upstream conserved region (UCR) characterizes the PDE4 family. Four separate genes (A-D) encode the PDE4 enzymes, and alternative splicing generates short or long isoforms of each gene. Long PDE4 isoforms contain both UCR1 and UCR2 while short PDE4 isoforms possess only UCR2. Both UCR domains are necessary for dimerization of PDE4 isoforms. The human PDE4C gene maps to chromosome 19p13.1. The splice variants include isoforms PDE4C1-7.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

CAMP-specific 3',5'-cyclic phosphodiesterase 4C; DPDE1; PDE21; DPDE1

Swiss Prot

Q08493

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 333-378 of Human PDE4C.

Conjugation

Unconjugated

Applications

WB ICC

Dilution

WB: 1:500~1:1000 ICC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 80 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

PDE4C polyclonal antibody detects endogenous levels of PDE4C protein.

Applications Notes

Western blot (WB) analysis of PDE4C polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:Mouse liver tissue lysate Lane3:H9C2 cell lysate