Kv3.1 polyclonal antibody
Product Specifications
Background
The human voltage-gated potassium (KV) channel KV3.1 gene maps to chromosome 11p15 and encodes a protein that resembles Drosophila Shaw subfamily channel types. KV channels regulate neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KV channels are multimers that contain channel activity-dependent alpha subunits and modulatory gamma subunits. Neuronal populations in the CNS coexpressing KV3.1 and KV3.3 influence fast repolarization of action potentials and enable neurons to fire repetitively at high frequencies. KV3 genes produce multiple splice variants in the 3' ends of respective transcript, which may influence normal spatial ion permeability of excitable membranes in the brain.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Potassium voltage-gated channel subfamily C member 1; NGK2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4; KCNC1
Swiss Prot
P48547
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 254-299 of Human Kv3.1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 58 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Kv3.1 polyclonal antibody detects endogenous levels of Kv3.1 protein.
Applications Notes
Western blot (WB) analysis of Kv3.1 polyclonal antibody at 1:500 dilution Lane1:Jurkat cell lysate Lane2:Raw264.7 cell lysate Lane3:H9C2 cell lysate
Host or Source
Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15400566 1 Vial
Lentiviral human DNAJC21 sgRNA gene knockout kit - Lentiviral human DNAJC21 sgRNA gene knockout kit (25)
Ask
View Details