GALK1 polyclonal antibody
Product Specifications
Background
Galactose kinase (GALK1), also often designated galactokinase, is important in the first step of the galactose metabolism pathway. GALK1, which belongs to the GHMP kinase family of proteins, is a crucial enzyme for galactose metabolism. Defects in the gene encoding for galactose kinase, GALK1, can cause galactosemia II, an autosomal recessive disorder characterized by congenital cataracts during infancy, often within the first two weeks of life. In the adult population it can cause presenile cataracts that are secondary to accumulation of galactitol in the lens of the eye.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Galactokinase; Galactose kinase; GALK1; GALK
Swiss Prot
P51570
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 4-49 of Human GALK1.
Conjugation
Unconjugated
Applications
WB IHC ICC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200 ICC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
GALK1 polyclonal antibody detects endogenous levels of GALK1 protein.
Applications Notes
Western blot (WB) analysis of GALK1 polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:sp2/0 cell lysate Lane3:Rat liver tissue lysate
Host or Source
Rabbit
Available Sizes
Curated Selection
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