YEATS2 polyclonal antibody
Product Specifications
Background
The YEATS domain-containing protein 2 (YEATS2) is a nuclear protein that is phosphorylated upon DNA damage by ATM or ATR and contains 1 YEATS domain. The gene encoding YEATS2 resides on chromosome 3, which contains about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B.
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
YEATS domain-containing protein 2; YETS2; KIAA1197
Swiss Prot
Q9ULM3
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 393-438 of Human YEATS2.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 150 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
YEATS2 polyclonal antibody detects endogenous levels of YEATS2 protein.
Applications Notes
Western blot (WB) analysis of YEATS2 pAb at 1:500 dilution Lane1:A2780 whole cell lysate (40ug) Lane2:MCF-7 whole cell lysate (40ug) Lane3:SK-OVCAR3 whole cell lysate (40ug) Lane4:HEK293T whole cell lysate (40ug) Lane5:A549 whole cell lysate (40ug)
Host or Source
Rabbit
CAS Number
9007-83-4
Available Sizes
Curated Selection
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