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Brn-3c polyclonal antibody

Product Specifications

Background

Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. Brn-3a has two functional transactivating domains, one at the amino terminus and one at the carboxy terminus. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

POU domain, class 4, transcription factor 3; Brain-specific homeobox/POU domain protein 3C; Brain-3C; Brn-3C; POU4F3; BRN3C

Swiss Prot

Q15319

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 263-308 of Human Brn-3c.

Conjugation

Unconjugated

Applications

WB

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 37 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

Brn-3c polyclonal antibody detects endogenous levels of Brn-3c protein.

Applications Notes

Western blot (WB) analysis of Brn-3c polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:Raw264.7 cell lysate Lane3:H9C2 cell lysate

Host or Source

Rabbit

Available Sizes

Frequently Asked Questions

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