ALS polyclonal antibody
Product Specifications
Background
The Insulin-like growth factor binding proteins, or IGFBPs, are a family of seven proteins that have co-evolved with the IGFs. IGFBPs serve as shuttle molecules for both IGF-I and IGF-II and confer a level of regulation to the IGF signaling system by influencing the bio-availability, concentration and distribution of IGFs in the extracellular environment. In human circulation, the IGF-binging protein complex requires ALS (IGFBP acid-labile subunit), an extracellular protein involved in receptor-ligand binding and cell adhesion. ALS, detected primarily in plasma, is involved in protein-protein interactions that result in the formation of protein complexes.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Insulin-like growth factor-binding protein complex acid labile subunit; IGFALS
Swiss Prot
P35858
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 177-222 of Human ALS.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 66 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ALS polyclonal antibody detects endogenous levels of ALS protein.
Applications Notes
Western blot (WB) analysis of ALS polyclonal antibody at 1:500 dilution Lane1:HEK293T cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat kidney tissue lysate
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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