Tensin-1 (phospho-Y483) polyclonal antibody
Product Specifications
Background
Tensin is involved in the maintenance of cellular structure by anchoring Actin filaments at the focal adhesion via F-Actin binding and capping activities. However, tensin also contains a Src homology 2 (SH2) domain and has the ability to be phosphorylated. Tensin is phosphorylated on tyrosine, serine, and threonine residues, suggesting that it might participate in signal transduction cascades. These diverse characteristics in a single molecule indicate that tensin may be an important link between the cytoskeleton and signal transduction pathways.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Tensin-1; TNS1; TNS
Swiss Prot
Q9HBL0
Reactivity
Human, Mouse
Immunogen
Synthetic phosphopeptide derived from human Tensin-1 around the phosphorylation site of Tyrosine 483.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Phosphorylation
Molecular Weight
~ 152, 230 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
P-Tensin-1 (Y483) polyclonal antibody detects endogenous levels of Tensin-2 protein when phosphorylated at Tyr483.
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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