Catalase (phospho-Y385) polyclonal antibody
Product Specifications
Background
Catalase is a peroxisome specific marker protein belonging to the catalase family. Defects in the gene encoding for the catalase protein can cause acatalasia, a disease characterized by the absence of catalase activity in red cells and associated with ulcerating oral lesions. Catalase is also an important regulator of oxidative stress and inflammation, and may contribute to the development of rheumatoid arthritis. Catalase, which can form a homotetramer, is found in all nearly all aerobically respiring organisms and functions in protecting cells from the toxic effects of hydrogen peroxide.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Catalase; CAT
Swiss Prot
P04040
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human Catalase around the phosphorylation site of Tyrosine 385.
Conjugation
Unconjugated
Related Pathways
AMPK Signaling Pathway
Applications
IHC
Dilution
IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Phosphorylation
Molecular Weight
~ 60 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
P-Catalase (Y385) polyclonal antibody detects endogenous levels of Catalase protein only when phosphorylated at Tyr385
Host or Source
Rabbit
Available Sizes
Frequently Asked Questions
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