CaMKIV (phospho-T196/200) polyclonal antibody

Product Specifications

Background

Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Calcium/calmodulin-dependent protein kinase type IV; CaMK IV; CaM kinase-GR; CAMK4; CAMK; CAMK-GR; CAMKIV

Swiss Prot

Q16566

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human CaMKIV around the phosphorylation site of Threonine 200.

Conjugation

Unconjugated

Applications

IHC

Dilution

IHC: 1:50~1:200

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Phosphorylation

Molecular Weight

~ 60 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

P-CaMKIV (T196/200) polyclonal antibody detects endogenous levels of human CaMKIV protein only when phosphorylated at Thr200. This antibody also detects mouse and rat CaMKIV protein when phosphorylated at the corresponding sites (Thr196) .