MGST1 (R74) polyclonal antibody
Product Specifications
Background
Microsomal glutathione transferase 1 (MGST1) is an abundant protein that catalyzes the conjugation of electrophilic compounds with glutathione, as well as the reduction of lipid hydroperoxides. The level of MGST1 mRNA in rat are highest in liver, while the levels of expression vary in non-hepatic tissues. In addition, the subcellular localization patterns of MGST1 are highly tissue specific. In hepatocytes and bile ducts, MGST1 is localized to the cytoplasm. MGST1 is localized to the nucleus in choroid plexus and primary spermatocytes and displays a granular cytoplasmic staining pattern in the adrenal medulla) . Also, focal staining of MGST1 is observed in the distal tubules and collecting ducts of the liver.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Microsomal glutathione S-transferase 1; Microsomal GST-1; Microsomal GST-I; MGST1; GST12; MGST
Swiss Prot
P10620
Reactivity
Human, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 41-90 of Human MGST1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 18 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MGST1 (R74) polyclonal antibody detects endogenous levels of MGST1 protein.
Applications Notes
Western blot (WB) analysis of MGST1 (R74) pAb at 1:1000 dilution Lane1:HepG2 whole cell lysate (20ug) Lane2:HCC827 whole cell lysate (10ug) Lane3:The Liver tissue lysate of Rat (40ug) Lane4:The Liver tissue lysate of Mouse (40ug) Lane5:3T3-L1 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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