Hox-B2 (P67) polyclonal antibody

Product Specifications

Background

Hoxb-1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the sonic hedgehog and Mash1 signaling pathways. Hoxb2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. Hoxb2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, Hoxb2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.

CAS Number

9007-83-4

Structure Composition

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Product Name Alternative

Homeobox protein Hox-B2; Homeobox protein Hox-2.8; Homeobox protein Hox-2H; K8; HOX2H; HOXB2

Swiss Prot

P14652

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 30-80 of Human Hox-B2.

Conjugation

Unconjugated

Applications

Dilution

WB: 1:500~1:1000

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Modification

Unmodification

Molecular Weight

~ 38 kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Notes

For research use only, not for use in diagnostic procedure.

Specificity

HoxB2 (P67) polyclonal antibody detects endogenous levels of HoxB2 protein.

Applications Notes

Western blot (WB) analysis of Hox-B2 (P67) pAb at 1:1000 dilution Lane1:K562 whole cell lysate (40ug) Lane2:The Embryo tissue lysate of Mouse (20ug) Lane3:PC12 whole cell lysate (10ug) Lane4:Hela whole cell lysate (40ug)