Dsg2 (V440) polyclonal antibody
Product Specifications
Background
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Desmoglein 2; 1829; DSG2; 125671; Q14126; CDHF5; HDGC; MGC117034; MGC117036; MGC117037; ; Mouse monoclonal [3G132] to Desmoglein 2; 1829; DSG2; 125671; Q14126; CDHF5; HDGC; MGC117034; MGC117036; MGC117037; ; Desmoglein-2
Swiss Prot
Q14126
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 408-456 of Human Dsg2.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 140 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Dsg2 (V440) polyclonal antibody detects endogenous levels of Dsg2 protein.
Applications Notes
Western blot (WB) analysis of Dsg2 (V440) pAb at 1:1000 dilution Lane1:Hela whole cell lysate (20ug) Lane2:The Embryo tissue lysate of Mouse (40ug) Lane3:SGC7901 whole cell lysate (40ug) Lane4:PC12 whole cell lysate (40ug)
Host or Source
Rabbit
Available Sizes
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